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Letter
Nature Genetics 39, 1403–1409 (1 November 2007) | doi:10.1038/ng.2007.1
DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans
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Abstract
Cancer is an age-related disease, and inhibiting insulin/insulin-like growth factor 1 (IGF-1) signaling extends lifespan and increases tumor resistance in C. elegans and mammals.
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