Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Brief Communication
Nature Genetics 39, 1197–1199 (1 October 2007) | doi:10.1038/ng2108
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15
&
Abstract
F cells measure the presence of fetal hemoglobin, a heritable quantitative trait in adults that accounts for substantial phenotypic diversity of sickle cell disease and β thalassemia. We applied a genome-wide association mapping strategy to individuals with contrasting extreme trait values and mapped a new F cell quantitative trait locus to BCL11A, which encodes a zinc-finger protein, on chromosome 2p15.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
