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Nature Genetics 39, 1190 - 1191 (2007)
doi:10.1038/ng1007-1190

Rhythm is not enough

Bernhard Horsthemke1

  1. Bernhard Horsthemke is at the Institut für Humangenetik, Universitätsklinikum Essen, Germany. e-mail: bernhard.horsthemke@uni-due.de


MAGEL2 is located in a cluster of imprinted genes on human chromosome 15 that is implicated in Prader-Willi syndrome (PWS). A new study shows that mice deficient for this gene show altered behavioral rhythmicity that resembles some features of PWS.

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RESEARCH

The imprinted gene Magel2 regulates normal circadian output

Nature Genetics Letter (01 Oct 2007)


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