Supplementary information

From the following article

Integrative molecular concept modeling of prostate cancer progression

Scott A Tomlins, Rohit Mehra, Daniel R Rhodes, Xuhong Cao, Lei Wang, Saravana M Dhanasekaran, Shanker Kalyana-Sundaram, John T Wei, Mark A Rubin, Kenneth J Pienta, Rajal B Shah & Arul M Chinnaiyan

Nature Genetics 39, 41 - 51 (2007)

doi:10.1038/ng1935

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Supplementary Fig. 1

Stromal contamination masks epithelial gene expression across prostate cancer profiling studies.

Supplementary Fig. 2

Validation of the prostate cancer progression signature.

Supplementary Fig. 3

Distinct expression patterns between the putative precursor lesions prostatic intraepithelial neoplasia and atrophic epithelium.

Supplementary Fig. 4

Marked overexpression of ETS family members through TMPRSS2:ETS gene fusions characterize the transition from prostatic intraepithelial neoplasia to prostate cancer in a majority of cases.

Supplementary Fig. 5

Molecular concepts analysis comparing clinically localized prostate cancer to hormone refractory metastatic prostate cancer.

Supplementary Table 1

Oligonucleotide primers.

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