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Letter

Nature Genetics 39, 113–119 (1 January 2007) | doi:10.1038/ng1930

A genome-wide map of diversity in Plasmodium falciparum

Sarah K Volkman , Pardis C Sabeti , David DeCaprio , Daniel E Neafsey , Stephen F Schaffner , Danny A Milner , Johanna P Daily , Ousmane Sarr , Daouda Ndiaye , Omar Ndir , Soulyemane Mboup , Manoj T Duraisingh , Amanda Lukens , Alan Derr , Nicole Stange-Thomann , Skye Waggoner , Robert Onofrio , Liuda Ziaugra , Evan Mauceli , Sante Gnerre , David B Jaffe , Joanne Zainoun , Roger C Wiegand , Bruce W Birren , Daniel L Hartl , James E Galagan , Eric S Lander & Dyann F Wirth

Genetic variation allows the malaria parasite Plasmodium falciparum to overcome chemotherapeutic agents, vaccines and vector control strategies and remain a leading cause of global morbidity and mortality. Here we describe an initial survey of genetic variation across the P.