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Letter
Nature Genetics - 38, 1049 - 1054 (2006)
Published online: 27 August 2006; | doi:10.1038/ng1871

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

Mingyao Li, Pelin Atmaca-Sonmez, Mohammad Othman, Kari E H Branham, Ritu Khanna, Michael S Wade, Yun Li, Liming Liang, Sepideh Zareparsi, Anand Swaroop & Gonçalo R Abecasis

Supplementary Fig. 1 (pdf 432K)
Analysis of Y402H and of SNPs selected in our stepwise search using the haplotype method of Valdes and Thomson (1997).

Supplementary Fig. 2 (pdf 84K)
Sensitivity of LAMP results to estimates of disease prevalence.

Supplementary Table 1 (pdf 116K)
Association test results for all SNPs.

Supplementary Table 2 (pdf 24K)
Genotype counts and allelic and genotypic association test results for all 84 SNPs.

Supplementary Table 3 (pdf 20K)
Genotype counts and mean allelic and genotypic test results in the 10 imputed datasets.

Supplementary Table 4 (pdf 12K)
Results using alternative approaches for SNP selection.

Supplementary Table 5 (pdf 16K)
Results of exhaustive search for the best SNP combination.

Supplementary Table 6 (pdf 12K)
Haplo-genotype counts for cases and controls.


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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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