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Letter

Nature Genetics 38, 931–935 (1 August 2006) | doi:10.1038/ng1833

Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification

Fabienne Cl|[eacute]|ard , Yuri Moshkin , Fran|[ccedil]|ois Karch & Robert K Maeda

A cis-regulatory region of nearly 300 kb controls the expression of the three bithorax complex (BX-C) homeotic genes: Ubx, abd-A and Abd-B. Interspersed between the numerous enhancers and silencers within the complex are elements called domain boundaries.