Nature Genetics 38, 813 - 818 (2006)
Published online: 4 June 2006; | doi:10.1038/ng1810
A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheepAlex Clop, Fabienne Marcq, Haruko Takeda, Dimitri Pirottin, Xavier Tordoir, Bernard Bibé, Jacques Bouix, Florian Caiment, Jean-Michel Elsen, Francis Eychenne, Catherine Larzul, Elisabeth Laville, Françoise Meish, Dragan Milenkovic, James Tobin, Carole Charlier&
Michel Georges Supplementary Fig. 1 (pdf 32K)
'Within–sire family' QTL analysis demonstrating the TR genotype of the three F1 rams. Supplementary Fig. 2 (pdf 112K)
Marker-assisted segregation analysis. Supplementary Fig. 3 (pdf 68K)
Comparing the amounts of GDF8 (MSTN) mRNA in skeletal muscle of Texel and wild-type sheep using real-time quantitative RT-PCR. Supplementary Fig. 4 (pdf 36K)
SNPs discovered in the ovine GDF8 (MSTN) gene and allelic frequencies in hypermuscled Texels and wild-type controls. Supplementary Fig. 5 (pdf 68K)
Sequence context of the polymorphic miRNA-GDF8 interaction in sheep. Supplementary Table 1 (pdf 28K)
Effects of the OAR2 QTL on muscularity, fat deposition and body composition significant at the genome-wide 5% level. Supplementary Table 2 (pdf 32K)
Genotypes of 42 Texel, 90 controls and four TR rams (three F1, one F2) for the 20 SNPs discovered in the GDF9 (MSTN) gene. Supplementary Table 3 (pdf 20K)
Primer sequences.
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