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Volume 38 Issue 6, June 2006

Evolving Helix #1 (3" x 3" x ") by Jo Ubogy (Ubogy@optonline.net) A nanowork from the Silvermine Guild Arts Center http://silvermineart.org/

Editorial

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Correspondence

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Book Review

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News & Views

  • Two new studies evaluate the extent to which widely used SNP platforms capture common variation in different populations, and they present strategies for improving power in whole-genome association studies using fixed marker sets. Their results suggest that genome-wide association studies are finally ready to move from theory to practice.

    • Christopher S Carlson
    News & Views
  • Flowering at the appropriate time is critical to ensure that plants complete sexual reproduction before the onset of winter in temperate habitats. A new study provides the first strong evidence that variation at a photoreceptor gene contributes to variation in flowering time and does so in a latitude-dependent manner.

    • Sarah Mathews
    News & Views
  • The identification of hundreds of thousands of clusters of transcriptional start sites, many located within internal exons of protein-coding genes, indicates that promoter sites are common and that transcriptional organization is complex. This transcriptional architecture implies that most genomic regions serve multiple functions.

    • Thomas R Gingeras
    News & Views
  • The process of gene expression is inherently stochastic and leads to differences in protein abundance from one cell to another. A new study shows that this protein noise is unexpectedly predictable, providing important new insights into the properties and origins of variability in gene expression.

    • Kristin Baetz
    • Mads Kærn
    News & Views
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Brief Communication

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Article

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Letter

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Corrigendum

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Supplement

  • microRNAs are a considerable part of the transcriptional output of the genomes of plants and animals, they regulate a large part of their transcriptomes, and they serve important regulatory functions in widespread biological activities.

    Supplement
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