A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis
Heiko Witt
,
Mikl|[oacute]|s Sahin-T|[oacute]|th
,
Olfert Landt
,
Jian-Min Chen
,
Thilo K|[auml]|hne
,
Joost PH Drenth
,
Zolt|[aacute]|n Kukor
,
Edit Szepessy
,
Walter Halangk
,
Stefan Dahm
,
Klaus Rohde
,
Hans-Ulrich Schulz
,
C|[eacute]|dric Le Mar|[eacute]|chal
,
Nejat Akar
,
Rudolf W Ammann
,
Kaspar Truninger
,
Mario Bargetzi
,
Eesh Bhatia
,
Carlo Castellani
,
Giulia Martina Cavestro
,
Milos Cerny
,
Giovanni Destro-Bisol
,
Gabriella Spedini
,
Hans Eiberg
,
Jan B M J Jansen
,
Monika Koudova
,
Eva Rausova
,
Milan Macek
,
N|[uacute]|ria Malats
,
Francisco X Real
,
Hans-J|[uuml]|rgen Menzel
,
Pedro Moral
,
Roberta Galavotti
,
Pier Franco Pignatti
,
Olga Rickards
,
Julius Spicak
,
Narcis Octavian Zarnescu
,
Wolfgang B|[ouml]|ck
,
Thomas M Gress
,
Helmut Friess
,
Johann Ockenga
,
Hartmut Schmidt
,
Roland Pf|[uuml]|tzer
,
Matthias L|[ouml]|hr
,
Peter Simon
,
Frank Ulrich Weiss
,
Markus M Lerch
,
Niels Teich
,
Volker Keim
,
Thomas Berg
,
Bertram Wiedenmann
,
Werner Luck
,
David Alexander Groneberg
,
Michael Becker
,
Thomas Keil
,
Andreas Kage
,
Jana Bernardova
,
Markus Braun
,
Claudia G|[uuml]|ldner
,
Juliane Halangk
,
Jonas Rosendahl
,
Ulrike Witt
,
Matthias Treiber
,
Renate Nickel
&
Claude F|[eacute]|rec
Abstract
Chronic pancreatitis is a common inflammatory disease of the pancreas. Mutations in the genes encoding cationic trypsinogen (PRSS1) and the pancreatic secretory trypsin inhibitor (SPINK1) are associated with chronic pancreatitis.
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