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Article
Nature Genetics - 38, 540 - 549 (2006)
Published online: 23 April 2006; | doi:10.1038/ng1781

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band

Jordi Frigola, Jenny Song, Clare Stirzaker, Rebecca A Hinshelwood, Miguel A Peinado & Susan J Clark

Supplementary Fig. 1 (pdf 356K)
Identification of a differentially methylated region in colorectal cancer using AIMS.

Supplementary Fig. 2 (pdf 288K)
Ten defined genes are located in 2q14.2.

Supplementary Fig. 3 (pdf 1M)
Direct genomic bisulfite sequencing across chromosome 2q14.2

Supplementary Fig. 4 (pdf 1M)
Genomic bisulfite sequencing of individual clones of the CpG islands across 2q14.2.

Supplementary Fig. 5 (pdf 1M)
Real-time RT-PCR and temperature dissociation profiles.

Supplementary Fig. 6 (pdf 1M)
Chromatin immunoprecipitation real-time PCR and temperature dissociation profiles.

Supplementary Table 1 (pdf 68K)
Primers used for bisulfite sequencing, RT-PCR and ChIP analysis.

Supplementary Methods (pdf 64K)


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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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