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Letter
Nature Genetics - 38, 576 - 582 (2006)
Published online: 2 April 2006; | doi:10.1038/ng1776

Systematic identification of human mitochondrial disease genes through integrative genomics

Sarah Calvo, Mohit Jain, Xiaohui Xie, Sunil A Sheth, Betty Chang, Olga A Goldberger, Antonella Spinazzola, Massimo Zeviani, Steven A Carr & Vamsi K Mootha

Supplementary Fig. 1 (pdf 652K)
Maestro and MitoPred prediction overlap.

Supplementary Fig. 2 (pdf 656K)
Mouse-to-human orthology mapping.

Supplementary Fig. 3 (pdf 764K)
Correlation between eight data sets.

Supplementary Table 1 (pdf 756K)
Computation of gold-standard nonmitochondrial protein Tapproxmito.

Supplementary Table 2 (xls 20K)
MS/MS validation.

Supplementary Table 3 (xls 24K)
Previously known nuclear genes underlying mitochondrial diseases.

Supplementary Table 4 (xls 9M)
Human protein predictions.

Supplementary Table 5 (xls 8M)
Mouse protein predictions.

Supplementary Methods (pdf 120K)


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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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