Nature Genetics 38, 479 - 483 (2006)
Published online: 19 March 2006; | doi:10.1038/ng1766
In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetesStephan Kissler, Patrick Stern, Kazue Takahashi, Kara Hunter, Laurence B Peterson
& Linda S Wicker Supplementary Fig. 1 (pdf 344K) Dose effect of protective alleles at Idd5.2 in the absence of protective alleles at Idd5.1. Supplementary Fig. 2 (pdf 244K) Variegated expression in pLL3.7 transgenic mice. Supplementary Fig. 3 (pdf 304K) Lentiviral construct expression in pLB-915 founder. Supplementary Fig. 4 (pdf 348K) Reduced expression caused by interference between lentiviral constructs. Supplementary Fig. 5 (pdf 360K)
Nramp1 silencing protects from experimental autoimmune encephalomyelitis (EAE). Supplementary Table 1 (pdf 12K) Primer sequences used for cloning and target sequences used for shRNA design.
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