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Letter
Nature Genetics 38, 479–483 (1 April 2006) | doi:10.1038/ng1766
In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes
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Abstract
Type 1 diabetes is an autoimmune disease influenced by multiple genetic loci. Although more than 20 insulin-dependent diabetes (Idd) loci have been implicated in the nonobese diabetic (NOD) mouse model, few causal gene variants have been identified.
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