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Letter
Nature Genetics 38, 228 - 233 (2005)
Published online: 25 December 2005; | doi:10.1038/ng1725

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

Jian-Fu Chen, Elizabeth M Mandel, J Michael Thomson, Qiulian Wu, Thomas E Callis, Scott M Hammond, Frank L Conlon & Da-Zhi Wang

Supplementary Fig. 1 (pdf 696K)
miRNA array analysis of C2C12 cells.

Supplementary Fig. 2 (pdf 1M)
Expression of miR-1, miR-133 and skeletal muscle differentiation marker genes in C2C12 cells.

Supplementary Fig. 3 (pdf 1M)
Expression of miR-1 and miR-133 in cardiac and skeletal muscle in adult mice and throughout development.

Supplementary Fig. 4 (pdf 148K)
Expression of miR-1 and miR-133 primary transcripts in cardiac and skeletal muscle.

Supplementary Fig. 5 (pdf 220K)
A miR-1 and miR-133 enhancer directs reporter gene expression in cardiac and skeletal muscle.

Supplementary Fig. 6 (pdf 556K)
Repression of a miR-133 sensor by miR-133 in C2C12 cells.

Supplementary Fig. 7 (pdf 128K)
Sequences of the miR-1 and miR-133 target sites in the 3' UTR of HDAC4 and SRF genes.

Supplementary Table 1 (pdf 92K)
Sequences of oligonucleotides used in this study.


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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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