New insights into the biological basis of genomic disorders
Simon R Myers & Steven A McCarroll
Simon R. Myers and Steven A. McCarroll are at the Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, Massachusetts 02139, USA. smyers@broad.mit.edu or smccarro@broad.mit.edu
Many clinical syndromes result from deletion or duplication of regions within the human genome. Two new studies demonstrate strong connections between such events and allelic recombination in humans, which in the future may enable researchers to better predict the locations of unstable genomic regions.
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