Anita Göndör and Rolf Ohlsson are at the Department of Development and Genetics, Evolution Biology Centre, Norbyvägan 18A, Uppsala University, SE-752 36 Uppsala, Sweden. Anita.Gondor@ebc.uu.se
A new study shows that during transcription, the TH2 interleukin gene cluster is organized into several small chromatin loops connected at their base by the protein SATB1. This first detailed glimpse of chromatin folding provides a new perspective on the coordination of cell type–specific gene expression.
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