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Letter

Nature Genetics 38, 1210–1215 (1 October 2006) | doi:10.1038/ng1878

Nucleosome positions predicted through comparative genomics

Ilya P Ioshikhes , Istvan Albert , Sara J Zanton & B Franklin Pugh

DNA sequence has long been recognized as an important contributor to nucleosome positioning, which has the potential to regulate access to genes. The extent to which the nucleosomal architecture at promoters is delineated by the underlying sequence is now being worked out.