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Nature Genetics - 38, 1102 - 1103 (2006)
doi:10.1038/ng1006-1102
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(Re)modeling the transcriptional enhancer

Marc S Halfon

Marc S. Halfon is in the Department of Biochemistry, State University of New York at Buffalo, Buffalo, New York 14214, USA, and the Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. mshalfon@buffalo.edu

Transcriptional cis-regulatory modules have a fundamental role in regulating eukaryotic gene expression. A new study shows how computational modeling can test hypotheses about how regulatory elements function, with results that challenge conventional views of their organization.

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See also: Article by Janssens et al.
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