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Letter

Nature Genetics 37, 953–957 (1 September 2005) | doi:10.1038/ng1627

The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair

Wendy L Bridge , Cassandra J Vandenberg , Roger J Franklin & Kevin Hiom

BRIP1 (also called BACH1) is a DEAH helicase that interacts with the BRCT domain of BRCA1 (refs. 1–6) and has an important role in BRCA1-dependent DNA repair and checkpoint functions.