Johan Paulsson is in the Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Wilberforce Rd., Cambridge CB3 0WA, UK. J.Paulsson@damtp.cam.ac.uk
Molecular noise, or random fluctuations in the levels of cellular components, arises spontaneously when there are small numbers of molecules and is transmitted to dependent processes. A new study shows how noise propagates through gene expression in yeast and shows that chromosomal position has a more central role than previously thought.
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