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Letter
Nature Genetics  37, 401 - 406 (2005)
Published online: 27 March 2005; | doi:10.1038/ng1538

Chfr is required for tumor suppression and Aurora A regulation

Xiaochun Yu, Katherine Minter-Dykhouse, Liviu Malureanu, Wei-Meng Zhao, Dongwei Zhang, Carolin J Merkle, Irene M Ward, Hideyuki Saya, Guowei Fang, Jan van Deursen & Junjie Chen

Supplementary Fig. 1 (pdf 192K)
Tumor-free survival of wild-type and Chfr-deficient mice (from 40-80 weeks).

Supplementary Fig. 2 (pdf 224K)
Spontaneous foci formation in Chfr-/- MEFs.

Supplementary Fig. 3 (pdf 144K)
Chfr does not ubiquitinate Aurora B in vivo.

Supplementary Fig. 4 (pdf 392K)
Endogenous Aurora A is ubiquitinated by Chfr.

Supplementary Table 1 (pdf 172K)
Organs affected by tumors in wild-type and Chfr-deficient mice (40-80 weeks).


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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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