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Letter

Nature Genetics 37, 429–434 (1 April 2005) | doi:10.1038/ng1529

Fine-scale recombination patterns differ between chimpanzees and humans

Susan E Ptak , David A Hinds , Kathrin Koehler , Birgit Nickel , Nila Patil , Dennis G Ballinger , Molly Przeworski , Kelly A Frazer & Svante P|[auml]||[auml]|bo

Recombination rates seem to vary extensively along the human genome. Pedigree analysis suggests that rates vary by an order of magnitude when measured at the megabase scale, and at a finer scale, sperm typing studies point to the existence of recombination hotspots.