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Letter
Nature Genetics 37, 401–406 (1 April 2005) | doi:10.1038/ng1538
Chfr is required for tumor suppression and Aurora A regulation
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Abstract
Tumorigenesis is a consequence of loss of tumor suppressors and activation of oncogenes. Expression of the mitotic checkpoint protein Chfr is lost in 20–50% of primary tumors and tumor cell lines.
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