David Sinclair is in the Department of Pathology, Harvard Medical School, Boston, Massachusetts, 02115 USA. david_sinclair@hms.harvard.edu
Sir2 deacetylases are believed to promote the survival and longevity of organisms during times of adversity. A new study shows that activation of Sir2 by small molecules called sirtuin-activating compounds increases neuronal survival in two different models of Huntington disease, possibly opening new avenues for treatment.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.