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Volume 37 Issue 10, October 2005

Cover art: Cluster III, 22 1/4" x 14" spray paint and charcoal on paper. http://www.evestockton.com

Volume 37 Issue 10

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Editorial

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Correspondence

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Meeting Report

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News & Views

  • A new study of mice lacking Prox1, a gene required for the formation of lymphatic endothelial cells, unveils a link between lymph fluid and fat deposition. These findings bring the lymphatic vascular system into the focus of obesity research.

    • Martin Schneider
    • Edward M Conway
    • Peter Carmeliet
    News & Views

  • Transcription-coupled nucleosome turnover provides an opportunity to incorporate new nucleosomes at active genes. Swapping nucleosomes that contain silencing marks with those that are more permissive for transcription may provide a mechanism for remembering the activity state of a gene through the cell cycle.

    • Jason D Lieb
    News & Views

  • Cancer metastasis has historically been viewed in the context of the mutational spectra arising during development of the primary cancer. The identification of a new modifier of cancer metastasis efficiency in mice provides experimental support for a predisposition model in which metastatic potential is viewed as a heritable trait influenced by host genetic polymorphisms.

    • David W Threadgill
    News & Views

  • Asymmetric division of stem cells results into two unequal daughter cells, only one of which resembles the parent stem cell. A new study provides genetic evidence in Drosophila melanogaster that the disturbance of this delicately balanced process in neuronal stem cells induces a cancer-like state.

    • Hans Clevers
    News & Views

  • The ability of crop plants to tolerate high salt concentrations is an agriculturally useful trait. A new study in rice shows that allelic variation in OsHKT8, which encodes a Na+ transporter, contributes to the enhanced capacity of a salt-tolerant variety to maintain shoot K+ homeostasis under NaCl stress.

    • Ana M Rus
    • Ray A Bressan
    • Paul M Hasegawa
    News & Views
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Research Highlights

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Brief Communication

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Article

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Letter

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