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Letter
Nature Genetics 36, 1014–1018 (1 September 2004) | doi:10.1038/ng1411
Gene loops juxtapose promoters and terminators in yeast
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Abstract
Mechanistic analysis of transcriptional initiation and termination by RNA polymerase II (PolII) indicates that some factors are common to both processes. Here we show that two long genes of Saccharomyces cerevisiae, FMP27 and SEN1, exist in a looped conformation, effectively bringing together their promoter and terminator regions.
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