Nature Genetics
36, 700 - 706 (2004)
Published online: 6 June 2004; | doi:10.1038/ng1376
Evidence for substantial fine-scale variation in recombination rates across the human genomeDana C Crawford, Tushar Bhangale, Na Li, Garrett Hellenthal, Mark J Rieder, Deborah A Nickerson
& Matthew StephensSupplementary Fig. 1 (pdf 128k)
Bayes Factors (BFs) summarizing the strength of the evidence for a hotspot in each gene, and each population sample, for simulated data with and without recombination hotspots. Supplementary Fig. 2 (pdf 128k)
Estimated intensity and location of hotspots, based on African-American sample (red) and European sample (green), for all genes. Supplementary Table 1 (pdf 7k)
Gene name, location, size, and number of SNPs ( 5% minor allele frequency), nucleotide diversity ( ), and G+C content. Supplementary Table 2 (pdf 5k)
Molecular function based on PANTHER terms. Supplementary Table 3 (pdf 10k)
Estimated background recombination rate ( ) per kilobase; map-based estimates (cM/Mb); and estimated average recombination rate per kilobase for each gene. Supplementary Table 4 (pdf 7k)
Sequence motifs and their occurrences within and outside hotspots. Supplementary Methods (pdf 10k)
Further details on Markov Chain Monte Carlo procedure and caveats on interpretation of LRs.
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