Mark A. Gillespie and Michael A. Rudnicki are at the Ottawa Health Research Institute, Molecular Medicine Program, Ottawa, Ontario K1H 8L6, Canada. mrudnicki@ohri.ca
Factors that modify chromatin are crucial for regulating gene expression, but what, in turn, regulates these factors? A new study highlights the importance of signaling cascades in recruiting chromatin-remodeling enzymes to specific promoters during muscle differentiation.
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