Xiangzhong Yang, X. Cindy Tian and William Fodor are at the Center for Regenerative Biology, University of Connecticut, 1392 Storrs Road, Storrs, Connecticut 06269, USA.
The discovery that a differentiated somatic cell can give rise to a new organism through nuclear transfer cloning touched off a revolution in genetics. A new study outlining how to target genes serially in cows ushers in a new era in large-animal genetics.
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