Valerie Reinke is in the Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA. valerie.reinke@yale.edu
The genetic composition of sex chromosomes has been deciphered, in part, through large-scale gene expression studies in different species. A new study in mice adds a missing piece of the puzzle: the composition of the X chromosome in mammals is influenced by inactivation of the sex chromosomes during male meiosis.
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