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News and Views
Nature Genetics  36, 113 - 114 (2004)
doi:10.1038/ng0204-113

Monitoring p53's pulse

John J Tyson

John J. Tyson is at Virginia Polytechnic Institute and State University, Blacksburg, Virginia 061-0406, USA. tyson@vt.edu

The tumor-suppressor protein p53 mediates the response of mammalian cells to DNA damage. Studies now show that DNA damage elicits quantal pulses of p53, with greater damage eliciting more pulses.

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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