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Letter

Nature Genetics 36, 1219–1224 (1 November 2004) | doi:10.1038/ng1458

X-linked inheritance of Fanconi anemia complementation group B

Amom Ruhikanta Meetei , Marieke Levitus , Yutong Xue , Annette L Medhurst , Michel Zwaan , Chen Ling , Martin A Rooimans , Patrick Bier , Maureen Hoatlin , Gerard Pals , Johan P de Winter , Weidong Wang & Hans Joenje

Fanconi anemia is an autosomal recessive syndrome characterized by diverse clinical symptoms, hypersensitivity to DNA crosslinking agents, chromosomal instability and susceptibility to cancer. Fanconi anemia has at least 11 complementation groups (A, B, C, D1, D2, E, F, G, I, J, L); the genes mutated in 8 of these have been identified.