1
Nazneen Rahman is in the Section of Cancer Genetics, The Institute of Cancer Research, Cotswold Rd, Sutton, Surrey SM2 5NG, UK. nazneen.rahman@icr.ac.uk.
2
Alan Ashworth is at The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Rd, London SW3 6JB, UK. alan.ashworth@icr.ac.uk.
A new study shows that Fanconi anemia complementation group B is caused by mutations in a previously uncharacterized gene located on the X chromosome. Its unique chromosomal localization identifies FANCB as a potential weak link in a key DNA-repair and tumor-suppressor pathway.
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