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| Editorial | Top |
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'Good citizenship' or good business? p1025 doi:10.1038/ng1004-1025 Full text | PDF
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| Correspondence | Top |
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The case for a global human genome epidemiology initiative pp1027 - 1028 Muin J Khoury doi:10.1038/ng1004-1027 Full text | PDF
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Phylogenetic validation of horizontal gene transfer? p1028 Mark van Passel, Aldert Bart, Yvonne Pannekoek
& Arie van der Ende doi:10.1038/ng1004-1028a Full text | PDF
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The use of genome annotation data and its impact on biological conclusions pp1028 - 1029 Hervé Tettelin
& Julian Parkhill doi:10.1038/ng1004-1028b Full text | PDF
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| Book Review | Top |
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An ancestor's influence p1031 Reviewed by: Joe Felsenstein doi:10.1038/ng1004-1031 Full text | PDF
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| News and Views | Top |
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Tracing microRNA patterns in mice pp1033 - 1034 John Cobb
& Denis Duboule doi:10.1038/ng1004-1033 Abstract | Full text | PDF
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See also: Letter by Mansfield et al. |
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How to make an ape brain pp1034 - 1036 Ajit Varki doi:10.1038/ng1004-1034 Abstract | Full text | PDF
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See also: Brief Communication by Burki & Kaessmann |
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Shifting insulator boundaries pp1036 - 1037 Sangkyun Jeong
& Karl Pfeifer doi:10.1038/ng1004-1036 Abstract | Full text | PDF
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See also: Letter by Yu et al. |
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Linking pathways in colorectal cancer pp1038 - 1039 Gijs R van den Brink doi:10.1038/ng1004-1038 Abstract | Full text | PDF
(95K)
See also: Letter by He et al. |
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Touching base p1041 doi:10.1038/ng1004-1041 Full text | PDF
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Research Highlights p1043 doi:10.1038/ng1004-1043 Full text | PDF
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| Review | Top |
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The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology pp1045 - 1051 Nelson Freimer
& Chiara Sabatti Published online: 28 September 2004 | doi:10.1038/ng1433 Abstract | Full text | PDF
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| Brief Communications | Top |
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Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation pp1053 - 1055 Inessa Grinberg, Hope Northrup, Holly Ardinger, Chitra Prasad, William B Dobyns
& Kathleen J Millen Published online: 29 August 2004 | doi:10.1038/ng1420 Abstract | Full text | PDF
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Metabolic gene−deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes pp1056 - 1058 Stephen S Fong
& Bernhard Ø Palsson Published online: 26 September 2004 | doi:10.1038/ng1432 Abstract | Full text | PDF
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Regulatory evolution across the protein interaction network pp1059 - 1060 Bernardo Lemos, Colin D Meiklejohn
& Daniel L Hartl Published online: 19 September 2004 | doi:10.1038/ng1427 Abstract | Full text | PDF
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Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux pp1061 - 1063 Fabien Burki
& Henrik Kaessmann Published online: 19 September 2004 | doi:10.1038/ng1431 Abstract | Full text | PDF
(117K)
| Supplementary Information See also: News and Views by Varki |
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| Article | Top |
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Active genes dynamically colocalize to shared sites of ongoing transcription pp1065 - 1071 Cameron S Osborne, Lyubomira Chakalova, Karen E Brown, David Carter, Alice Horton, Emmanuel Debrand, Beatriz Goyenechea, Jennifer A Mitchell, Susana Lopes, Wolf Reik
& Peter Fraser Published online: 07 September 2004 | doi:10.1038/ng1423 Abstract | Full text | PDF
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| Letters | Top |
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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise pp1073 - 1078 Joshua T Mendell, Neda A Sharifi, Jennifer L Meyers, Francisco Martinez-Murillo
& Harry C Dietz Published online: 26 September 2004 | doi:10.1038/ng1429 Abstract | Full text | PDF
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MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression pp1079 - 1083 Jennifer H Mansfield, Brian D Harfe, Robert Nissen, John Obenauer, Jalagani Srineel, Aadel Chaudhuri, Raphael Farzan-Kashani, Michael Zuker, Amy E Pasquinelli, Gary Ruvkun, Phillip A Sharp, Clifford J Tabin
& Michael T McManus Published online: 12 September 2004 | doi:10.1038/ng1421 Abstract | Full text | PDF
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See also: News and Views by Cobb & Duboule |
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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia pp1084 - 1089 C. Graux, J. Cools, C. Melotte, H. Quentmeier, A. Ferrando, R. Levine, J.R. Vermeesch, M. Stul, B. Dutta, N. Boeckx, A. Bosly, P. Heimann, A. Uyttebroeck, N. Mentens, R. Somers, R.A.F. MacLeod, H.G. Drexler, A.T. Look, D.G. Gilliland, L. Michaux, P. Vandenberghe, I. Wlodarska, Peter Marynen
& Anne Hagemeijer Published online: 12 September 2004 | doi:10.1038/ng1425 Abstract | Full text | PDF
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A module map showing conditional activity of expression modules in cancer pp1090 - 1098 Eran Segal, Nir Friedman, Daphne Koller
& Aviv Regev Published online: 26 September 2004 | doi:10.1038/ng1434 Abstract | Full text | PDF
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The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome pp1099 - 1104 Prasanna M Bhende, William T Seaman, Henri-Jacques Delecluse
& Shannon C Kenney Published online: 12 September 2004 | doi:10.1038/ng1424 Abstract | Full text | PDF
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Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation pp1105 - 1110 Wenqiang Yu, Vasudeva Ginjala, Vinod Pant, Igor Chernukhin, Joanne Whitehead, France Docquier, Dawn Farrar, Gholamreza Tavoosidana, Rituparna Mukhopadhyay, Chandrasekhar Kanduri, Mitsuo Oshimura, Andrew P Feinberg, Victor Lobanenkov, Elena Klenova
& Rolf Ohlsson Published online: 07 September 2004 | doi:10.1038/ng1426 Abstract | Full text | PDF
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See also: News and Views by Jeong & Pfeifer |
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A specific requirement for PDGF-C in palate formation and PDGFR- signaling pp1111 - 1116 Hao Ding, Xiaoli Wu, Hans Boström, Injune Kim, Nicole Wong, Bonny Tsoi, Meredith O'Rourke, Gou Young Koh, Philippe Soriano, Christer Betsholtz, Thomas C Hart, Mary L Marazita, L L Field, Patrick P L Tam
& Andras Nagy Published online: 07 September 2004 | doi:10.1038/ng1415 Abstract | Full text | PDF
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BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt− -catenin signaling pp1117 - 1121 Xi C He, Jiwang Zhang, Wei-Gang Tong, Ossama Tawfik, Jason Ross, David H Scoville, Qiang Tian, Xin Zeng, Xi He, Leanne M Wiedemann, Yuji Mishina
& Linheng Li Published online: 19 September 2004 | doi:10.1038/ng1430 Abstract | Full text | PDF
(871K)
| Supplementary Information See also: News and Views by van den Brink |
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Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males pp1122 - 1125 Jason A Wilder, Sarah B Kingan, Zahra Mobasher, Maya Metni Pilkington
& Michael F Hammer Published online: 19 September 2004 | doi:10.1038/ng1428 Abstract | Full text | PDF
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| Corrigenda | Top |
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Corrigendum: Biased biological functions of horizontally transfered genes in prokaryotic genomes p1126 Y Nakamura, T Itoh, H Matsuda
& T Gojobori doi:10.1038/ng1004-1126a Full text | PDF
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Corrigendum: Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome p1126 R J Ferland, W Eyaid, R V Collura, L D Tully, R S Hill, D Al-Nouri, A Al-Rumayyan, M Topcu, G Gascon, A Bodell, Y Y Shugart, M Ruvolo
& C A Walsh doi:10.1038/ng1004-1126b Full text | PDF
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Corrigendum: Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm p1126 L Mandal, U Banerjee
& V Hartenstein doi:10.1038/ng1004-1126c Full text | PDF
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