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News and Views
Nature Genetics  35, 113 - 114 (2003)
doi:10.1038/ng1003-113

FANCL, as in ligase

Markus Grompe

Markus Grompe is at Oregon Health & Sciences University, Molecular and Medical Genetics, 3181 SW Sam Jackson Pk Rd, Portland, Oregon 97239, USA. grompem@ohsu.edu

Biochemical purification has identified a new component of the Fanconi anemia complex. The protein has ubiquitin ligase activity and may be the long-sought enzyme responsible for monoubiquitination of FANCD2.

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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