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Nature Genetics  35, 15 - 16 (2003)
doi:10.1038/ng0903-15

Alu: a parasite's parasite?

Carl W Schmid

The author is in the Molecular and Cellular Biology Section, University of California-Davis, Davis, California 95616-8535, USA. cwschmid@ucdavis.edu

The technical problem of detecting the retrotransposition—amplification and genomic dispersion of sequences through an RNA intermediate—of Pol III−directed transcripts has been solved. This provides a long-sought experimental system to learn how Alu repeats amplified to a high copy number in human DNA.

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REFERENCE
Chromosomes: Noncoding DNA (including Satellite DNA)
Nature Encyclopaedia of Life Sciences

RESEARCH
Human Alu element retrotransposition induced by genotoxic stress
Nature Genetics Brief Communications (01 Nov 2003)
LINE-mediated retrotransposition of marked Alu sequences
Nature Genetics Article (01 Sep 2003)
Human L1 element target-primed reverse transcription in vitro
The EMBO Journal Article (01 Nov 2002)

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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