Genomic profiling to promote a healthy lifestyle: not ready for prime timepp347 - 350 Susanne B Haga, Muin J Khoury
& Wylie Burke doi:10.1038/ng0803-347 Abstract|Full text|PDF
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Chromosome aberrations in solid tumorspp369 - 376 Donna G Albertson, Colin Collins, Frank McCormick
& Joe W Gray Published online: 30 July 2003|doi:10.1038/ng1215 Abstract|Full text|PDF
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Essentiality, not expressiveness, drives gene-strand bias in bacteriapp377 - 378 Eduardo P C Rocha
& Antoine Danchin Published online: 06 July 2003|doi:10.1038/ng1209 Abstract|Full text|PDF
(179K)
|Supplementary Information
Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcificationpp379 - 381 Frank Rutsch, Nico Ruf, Sucheta Vaingankar, Mohammad R. Toliat, Anita Suk, Wolfgang Höhne, Galen Schauer, Mandy Lehmann, Tony Roscioli, Dirk Schnabel, Jörg T. Epplen, Alex Knisely, Andrea Superti-Furga, James McGill, Marco Filippone, Alan R. Sinaiko, Hillary Vallance, Bernd Hinrichs, Wendy Smith, Merry Ferre, Robert Terkeltaub
& Peter Nürnberg Published online: 27 July 2003|doi:10.1038/ng1221 Abstract|Full text|PDF
(115K)
|Supplementary Information
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic deathpp383 - 394 Diether Lambrechts, Erik Storkebaum, Masafumi Morimoto, Jurgen Del-Favero, Frederik Desmet, Stefan L Marklund, Sabine Wyns, Vincent Thijs, Jörgen Andersson, Ingrid van Marion, Ammar Al-Chalabi, Stephanie Bornes, Rhiannon Musson, Valerie Hansen, Lars Beckman, Rolf Adolfsson, Hardev Singh Pall, Hervé Prats, Severine Vermeire, Paul Rutgeerts, Shigehiro Katayama, Takuya Awata, Nigel Leigh, Loïc Lang-Lazdunski, Mieke Dewerchin, Christopher Shaw, Lieve Moons, Robert Vlietinck, Karen E Morrison, Wim Robberecht, Christine Van Broeckhoven, Désiré Collen, Peter M Andersen
& Peter Carmeliet Published online: 06 July 2003|doi:10.1038/ng1211 Abstract|Full text|PDF
(1,335K)
|Supplementary Information See also:News and Views by Cleveland
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and humanpp403 - 412 Amanda Ewart-Toland, Paraskevi Briassouli, John P de Koning, Jian-Hua Mao, Jinwei Yuan, Florence Chan, Lucy MacCarthy-Morrogh, Bruce A J Ponder, Hiroki Nagase, John Burn, Sarah Ball, Maria Almeida, Spiros Linardopoulos
& Allan Balmain Published online: 27 July 2003|doi:10.1038/ng1220 Abstract|Full text|PDF
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See also:News and Views by Dove
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determinationpp413 - 420 Edgar A Otto, Bernhard Schermer, Tomoko Obara, John F O'Toole, Karl S Hiller, Adelheid M Mueller, Rainer G Ruf, Julia Hoefele, Frank Beekmann, Daniel Landau, John W Foreman, Judith A Goodship, Tom Strachan, Andreas Kispert, Matthias T Wolf, Marie F Gagnadoux, Hubert Nivet, Corinne Antignac, Gerd Walz, Iain A Drummond, Thomas Benzing
& Friedhelm Hildebrandt Published online: 20 July 2003|doi:10.1038/ng1217 Abstract|Full text|PDF
(1,561K)
|Supplementary Information See also:News and Views by Watnick & Germino
Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31pp421 - 428 Philomena Mburu, Mirna Mustapha, Anabel Varela, Dominique Weil, Aziz El-Amraoui, Ralph H Holme, Andreas Rump, Rachel E Hardisty, Stéphane Blanchard, Roney S Coimbra, Isabelle Perfettini, Nick Parkinson, Ann-Marie Mallon, Pete Glenister, Mike J Rogers, Adam J Paige, Lee Moir, Jo Clay, Andre Rosenthal, Xue Zhong Liu, Gonzalo Blanco, Karen P Steel, Christine Petit
& Steve D M Brown Published online: 29 June 2003|doi:10.1038/ng1208 Abstract|Full text|PDF
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Dopa decarboxylase (Ddc) affects variation in Drosophila longevitypp429 - 433 Maria De Luca, Nataliya V Roshina, Gretchen L Geiger-Thornsberry, Richard F Lyman, Elena G Pasyukova
& Trudy F C Mackay Published online: 27 July 2003|doi:10.1038/ng1218 Abstract|Full text|PDF
(317K)
|Supplementary Information See also:News and Views by Curtsinger
Mutations in the genes encoding 11-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiencypp434 - 439 Nicole Draper, Elizabeth A Walker, Iwona J Bujalska, Jeremy W Tomlinson, Susan M Chalder, Wiebke Arlt, Gareth G Lavery, Oliver Bedendo, David W Ray, Ian Laing, Ewa Malunowicz, Perrin C White, Martin Hewison, Philip J Mason, John M Connell, Cedric H L Shackleton
& Paul M Stewart Published online: 13 July 2003|doi:10.1038/ng1214 Abstract|Full text|PDF
(568K)
|Supplementary Information
Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP poolspp440 - 445 Takashi Kimura, Satoshi Takeda, Yoji Sagiya, Mitsukazu Gotoh, Yusuke Nakamura
& Hirofumi Arakawa Published online: 13 July 2003|doi:10.1038/ng1212 Abstract|Full text|PDF
(1,450K)
|Supplementary Information
Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the -thalassemia myelodysplasia syndrome (ATMDS)pp446 - 449 Richard J Gibbons, Andrea Pellagatti, David Garrick, William G Wood, Nicola Malik, Helena Ayyub, Cordelia Langford, Jacqueline Boultwood, James S Wainscoat
& Douglas R Higgs Published online: 13 July 2003|doi:10.1038/ng1213 Abstract|Full text|PDF
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Formation of stable epialleles and their paramutation-like interaction in tetraploid Arabidopsis thalianapp450 - 454 Ortrun Mittelsten Scheid, Karin Afsar
& Jerzy Paszkowski Published online: 06 July 2003|doi:10.1038/ng1210 Abstract|Full text|PDF
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Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosispp455 - 459 Heike Olbrich, Manfred Fliegauf, Julia Hoefele, Andreas Kispert, Edgar Otto, Andreas Volz, Matthias T Wolf, Gürsel Sasmaz, Ute Trauer, Richard Reinhardt, Ralf Sudbrak, Corinne Antignac, Norbert Gretz, Gerd Walz, Bernhard Schermer, Thomas Benzing, Friedhelm Hildebrandt
& Heymut Omran Published online: 20 July 2003|doi:10.1038/ng1216 Abstract|Full text|PDF
(361K)
|Supplementary Information See also:News and Views by Watnick & Germino
A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophypp460 - 463 Tsuyoshi Kashima
& James L Manley Published online: 29 June 2003|doi:10.1038/ng1207 Abstract|Full text|PDF
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Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leykemiap464 M Tartaglia, C M Niemeyer, A Fragale, X Song, J Buechner, A Jung, K Hählen, H Hasle, J D Licht
& B D Gelb doi:10.1038/ng0803-464 Full text|PDF
(181K)
Gene expression phenotypic models that predict the activity of oncogenic pathwaysp465 E Huang, S Ishida, J Pittmann, H Dressman, A Bild, M Kloos, M D'Amico, R G Pestell, M West
& J R Nevins doi:10.1038/ng0803-465 Full text|PDF
(366K)
-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency
-thalassemia myelodysplasia syndrome (ATMDS)
