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Nature Genetics  34, 360 - 361 (2003)
doi:10.1038/ng0803-360

Ensuring enhancer fidelity

Robert K Maeda & François Karch

Robert K. Maeda and François Karch are in the Department of Zoology and Animal Biology, University of Geneva, Geneva, Switzerland. francois.karch@zoo.unige.ch

Breaking the bond between an enhancer and a promoter has serious biological consequences. A recent study describes a new chromatin insulator in the Drosophila melanogaster Antennapedia complex (ANTC) that may ensure that nearby enhancers remain faithful to their respective promoters.

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REFERENCE
Drosophila Embryo: Homeotic Genes in Specification of the Anterior–Posterior Axis
Nature Encyclopaedia of Life Sciences

RESEARCH
A novel boundary element may facilitate independent gene regulation in the Antennapedia complex of Drosophila
The EMBO Journal Article (16 Jun 2003)

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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