Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Letter
Nature Genetics 34, 199–202 (1 June 2003) | doi:10.1038/ng1162
Trans allele methylation and paramutation-like effects in mice
&
Abstract
In mammals, imprinted genes have parent-of-origin–specific patterns of DNA methylation that cause allele-specific expression. At Rasgrf1 (encoding RAS protein-specific guanine nucleotide-releasing factor 1), a repeated DNA element is needed to establish methylation and expression of the active paternal allele.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
