Division of Molecular Bioscience, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia frances.shannon@anu.edu.au
The spatial organization of the interphase nucleus is related to the differentiation state of the cell and has a role in establishing tissue-specific patterns of gene expression. Investigation of a tissue-specific nuclear protein has identified a new mechanism of cell-specific gene regulation that links nuclear architecture, chromatin structure and gene transcription.
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