Nature Genetics33, 437 - 438 (2003)
Published online: 17 March 2003; | doi:10.1038/ng1135
Neurotoxic esterase: not so toxic?
James P. O'Callaghan
Molecular Neurotoxicology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, Centers for Disease Control and Prevention−NIOSH, Morgantown, West Virginia 26505, USA. jdo5@cdc.gov
An altered form of an esterase has been implicated in the development of neurotoxicity after exposure to organophosphates. Mice deficient in this enzyme should be less susceptible to toxicity, but the opposite turns out to be the case.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated
