Center For RNA Biology, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA. jkeene@micro.mc.duke.edu
A new study shows that cellular mRNAs can be organized and exported from the nucleus as functionally related groups by RNA-binding proteins, possibly corresponding to specific gene-expression networks activated by transcription factors. The combinatorial assortment of mRNAs as functional subsets has the potential to generate a variety of complex phenotypes from a modest number of genes.
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