1
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98125, USA.
2
Department of Radiation Oncology, University of Washington Medical School, Seattle, Washington 98195, USA.
Enhancer elements act from distal regions to mediate the transcription of genes. A novel combination of FISH and ChIP techniques may provide new insight into the mechanism by which enhancer elements exert their control. Application of the technique to the Hbb (encoding -globin) locus control region (LCR) suggests that elements of the LCR may be in close proximity to the transcribed -globin genes.
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