Medical applications of haplotype-based SNP maps: learning to walk before we runp353 Eric Lai, Clive Bowman, Aruna Bansal, Arlene Hughes, Michael Mosteller
& Allen D. Roses doi:10.1038/ng1102-353 Full text|PDF
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Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomaspp355 - 357 Keisuke Kurose, Kristie Gilley, Satoshi Matsumoto, Peter H. Watson, Xiao-Ping Zhou
& Charis Eng Published online: 15 October 2002|doi:10.1038/ng1013 Abstract|Full text|PDF
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Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humanspp359 - 369 Kunio Kitamura, Masako Yanazawa, Noriyuki Sugiyama, Hirohito Miura, Akiko Iizuka-Kogo, Masatomo Kusaka, Kayo Omichi, Rika Suzuki, Yuko Kato-Fukui, Kyoko Kamiirisa, Mina Matsuo, Shin-ichi Kamijo, Megumi Kasahara, Hidefumi Yoshioka, Tsutomu Ogata, Takayuki Fukuda, Ikuko Kondo, Mitsuhiro Kato, William B. Dobyns, Minesuke Yokoyama
& Ken-ichirou Morohashi Published online: 15 October 2002|doi:10.1038/ng1009 Abstract|Full text|PDF
(2,199K)
|Supplementary Information See also:News and Views by Reiner
Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencingpp370 - 377 Akatsuki Kimura, Takashi Umehara
& Masami Horikoshi Published online: 15 October 2002|doi:10.1038/ng993 Abstract|Full text|PDF
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Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatinpp378 - 383 Noriyuki Suka, Kunheng Luo
& Michael Grunstein Published online: 15 October 2002|doi:10.1038/ng1017 Abstract|Full text|PDF
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The K−Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosumpp384 - 392 Heidi C. Howard, David B. Mount, Daniel Rochefort, Nellie Byun, Nicolas Dupré, Jianming Lu, Xuemo Fan, Luyan Song, Jean-Baptiste Rivière, Claude Prévost, Jürgen Horst, Alessandro Simonati, Beate Lemcke, Rick Welch, Roger England, Frank Q. Zhan, Adriana Mercado, William B. Siesser, Alfred L. George Jr, Michael P. McDonald, Jean-Pierre Bouchard, Jean Mathieu, Eric Delpire
& Guy A. Rouleau Published online: 07 October 2002|doi:10.1038/ng1002 Abstract|Full text|PDF
(719K)
|Supplementary Information
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcriptionpp393 - 396 Raffaella Santoro, Junwei Li
& Ingrid Grummt Published online: 07 October 2002|doi:10.1038/ng1010 Abstract|Full text|PDF
(447K)
See also:News and Views by Pikaard & Lawrence
The human TAS2R16 receptor mediates bitter taste in response to -glucopyranosidespp397 - 401 Bernd Bufe, Thomas Hofmann, Dietmar Krautwurst, Jan-Dirk Raguse
& Wolfgang Meyerhof Published online: 15 October 2002|doi:10.1038/ng1014 Abstract|Full text|PDF
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Genome sequence of the endocellular obligate symbiont of tsetse flies, Wigglesworthia glossinidiapp402 - 407 Leyla Akman, Atsushi Yamashita, Hidemi Watanabe, Kenshiro Oshima, Tadayoshi Shiba, Masahira Hattori
& Serap Aksoy Published online: 03 September 2002|doi:10.1038/ng986 Abstract|Full text|PDF
(158K)
See also:News and Views by Wren
Requirement of Bmpr1a for Müllerian duct regression during male sexual developmentpp408 - 410 Soazik P. Jamin, Nelson A. Arango, Yuji Mishina, Mark C. Hanks
& Richard R. Behringer Published online: 07 October 2002|doi:10.1038/ng1003 Abstract|Full text|PDF
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A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesionspp411 - 414 Sheila Harroch, Glaucia C. Furtado, Wolfgang Brueck, Jack Rosenbluth, Juan Lafaille, Moses Chao, Joseph D. Buxbaum
& Joseph Schlessinger Published online: 30 September 2002|doi:10.1038/ng1004 Abstract|Full text|PDF
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A role for the Rb family of proteins in controlling telomere lengthpp415 - 419 Marta García-Cao, Susana Gonzalo, Douglas Dean
& María A. Blasco Published online: 15 October 2002|doi:10.1038/ng1011 Abstract|Full text|PDF
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Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific proteasepp420 - 425 Scott M. Wilson, Bula Bhattacharyya, Rivka A. Rachel, Vincenzo Coppola, Lino Tessarollo, Deborah B. Householder, Colin F. Fletcher, Richard J. Miller, Neal G. Copeland
& Nancy A. Jenkins Published online: 07 October 2002|doi:10.1038/ng1006 Abstract|Full text|PDF
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Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1pp426 - 431 Galina V. Fitzpatrick, Paul D. Soloway
& Michael J. Higgins Published online: 09 September 2002|doi:10.1038/ng988 Abstract|Full text|PDF
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Detection of regulatory variation in mouse genespp432 - 437 Christopher R. Cowles, Joel N. Hirschhorn, David Altshuler
& Eric S. Lander Published online: 15 October 2002|doi:10.1038/ng992 Abstract|Full text|PDF
(195K)
|Supplementary Information
Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timingpp438 - 442 Dirk Schübeler, David Scalzo, Charles Kooperberg, Bas van Steensel, Jeffrey Delrow
& Mark Groudine Published online: 30 September 2002|doi:10.1038/ng1005 Abstract|Full text|PDF
(419K)
|Supplementary Information See also:News and Views by Gilbert
A missense mutation in Tbce causes progressive motor neuronopathy in micepp443 - 447 Natalia Martin, Jean Jaubert, Pierre Gounon, Eduardo Salido, Georg Haase, Marek Szatanik
& Jean-Louis Guénet Published online: 21 October 2002|doi:10.1038/ng1016 Abstract|Full text|PDF
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Mutation of TBCE causes hypoparathyroidism− retardation−dysmorphism and autosomal recessive Kenny−Caffey syndromepp448 - 452 The HRD/Autosomal Recessive Kenny−Caffey Syndrome Consortium: Group 1: Ruti Parvari, Eli Hershkovitz, Nili Grossman, Rafael Gorodischer, Bart Loeys, Alexandra Zecic, Geert Mortier, Simon Gregory
& Reuven SharonyGroup 2: Marios Kambouris, Nadia Sakati
& Brian F. MeyerGroup 3: Aida I. Al Aqeel, Abdul Karim Al Humaidan, Fatma Al Zanhrani, Abdulrahman Al Swaid
& Johara Al OthmanGroup 4: George A. Diaz, Rory Weiner, K. Tahseen S. Khan, Ronald Gordon
& Bruce D. Gelb Published online: 21 October 2002|doi:10.1038/ng1012 Abstract|Full text|PDF
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Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumorspp453 - 458 Giuseppe Zardo, Maarit I. Tiirikainen, Chibo Hong, Anjan Misra, Burt G. Feuerstein, Stanislav Volik, Colin C. Collins, Kathleen R. Lamborn, Andrew Bollen, Daniel Pinkel, Donna G. Albertson
& Joseph F. Costello Published online: 30 September 2002|doi:10.1038/ng1007 Abstract|Full text|PDF
(729K)
|Supplementary Information
Computational identification of promoters and first exons in the human genomep459 R V Davuluri, I Grosse
& M Q Zhang doi:10.1038/ng1102-459a Full text|PDF
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High-throughput retroviral tagging to identify components of specific signaling pathways in cancerp459 H Mikkers, J Allen, P Knipscheer, L Romeyn, A Hart, E Vink
& A Berns doi:10.1038/ng1102-459b Full text|PDF
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The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystinp459 G Mollet, R Salomon, O Gribouval, F Silbermann, D Bacq, G Landthaler, D Milford, A Nayir, G Rizzoni, C Antignac
& S Saunier doi:10.1038/ng1102-459c Full text|PDF
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-glucopyranosides
