Shinji Kondo1, 19, Brian C. Schutte1, 2, 19, Rebecca J. Richardson3, 20, Bryan C. Bjork4, 20, Alexandra S. Knight3, Yoriko Watanabe1, Emma Howard3, Renata L.L. Ferreira de Lima5, Sandra Daack-Hirsch1, Achim Sander6, 21, Donna M. McDonald-McGinn7, Elaine H. Zackai7, Edward J. Lammer8, Arthur S. Aylsworth9, Holly H. Ardinger10, Andrew C. Lidral11, Barbara R. Pober12, Lina Moreno13, Mauricio Arcos-Burgos14, Consuelo Valencia14, Claude Houdayer15, Michel Bahuau15, 16, Danilo Moretti-Ferreira5, Antonio Richieri-Costa17, Michael J. Dixon3
& Jeffrey C. Murray1, 2, 181
Department of Pediatrics, The University of Iowa, Iowa City, Iowa 52242, USA.
2
Interdisciplinary PhD Program in Genetics, The University of Iowa, Iowa City, Iowa 52242, USA.
3
School of Biological Sciences and Department of Dental Medicine and Surgery, University of Manchester, Oxford Road, Manchester, UK.
4
Harvard University, Brigham and Women's Hospital, Boston, Massachusetts, USA.
5
Servico de Aconselhamento, Genetico da Universidade Estadual Paulista, Botucatu S.P., Brazil.
6
Clinic of Oral-Maxillofacial Surgery, University of Hamburg, Hamburg, Germany.
7
Division of Human Genetics and Molecular Biology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
8
Medical Genetics, Children's Hospital, Oakland, California, USA.
9
Department of Pediatrics and Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.
10
Department of Pediatrics, University of Kansas, Children's Medical Center, Kansas City, Kansas, USA.
11
Department of Orthodontics, The University of Iowa, Iowa City, Iowa, USA.
12
Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.
13
PhD Program in Oral Sciences, The University of Iowa, Iowa City, Iowa, USA.
14
Universidad de Antioquia, Medellin, Colombia.
15
Service de Biochimie et Biologie Moléculaire, Hôpital d'Enfants Armand-Trousseau, Paris, France.
16
Service de Chirurgie Maxillofaciale et Plastique, Stomatologie, Hôpital d'Enfants Armand-Trousseau, Paris, France.
17
Departmento de Genetica Clinica, Hospital de Pesquisa e Reabilitacao de Lesoes Labio-Palatais, Universidade de São Paulo, Bauru, Brazil.
18
Department of Biology, The University of Iowa, Iowa City, Iowa 52242, USA.
19
These two authors contributed equally to this work.
20
These two authors contributed equally to this work.
21
Deceased.
Correspondence should be addressed to Jeffrey C. Murray jeff-murray@uiowa.edu