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Mutant
Hi#
Other Insertional Alleles
Phenotype Description
Picture(s)
Gene Product (known ENU-induced mutant)
Accession #
Linkage, Transcript levels (shown as % transcript reduction in mutant by RT or in situ)
References
783

1703

 

 

 d2, severe brain and eye necrosis*. DNA polymerase epsilon subunit B
Acc. AF506228		 44/44= mutant
0/93= wildtype		  
800a 2191 d3, smaller head and eyes. Chaperonin containing TCP-1 complex, eta subunit
Acc. AF506229		 67/67= mutant
0/113= wildtype		  
821a 2144 d1, CNS and eye necrosis*. Novel protein
Acc. AF506230		 50/50= mutant
0/47= wildtype
RT= no wildtype transcript detected		  
887   d3, reduced circulation in tail. d4, smaller head, eyes, and body, jaw and arches reduced. Mitochondrial inner membrane translocating protein, TIMM23
Acc. AF506231		 21/21= mutant
0/24= wildtype		  
889  

 

 

 d5, swim bladder does not inflate. TAF7 RNA polymerase II, TBP-associated factor, 55kd
Acc. AF506232		 24/24= mutant
0/24= wildtype		  
904   d2, disorganized brain and neural tube, cells appear loosely packed. d3, tail bent, smaller head, very small or absent otoliths. Novel protein
Acc. AF506233		 24/24= mutant
0/24= wildtype
RT= no transcript detected		  
923   d3, small melanophores and irridophores, no xanthophores. d4, brain necrosis* and pericardiac edema. Vacuolar H(+)-ATPase SFD beta isoform
Acc. AF506234		 33/33= mutant
0/66= wildtype
RT>99%		  
954 3357 d4, jaw size reduced, cartilage does not stain with alcian blue, yet cartilage cells are present when sectioned.
UDP-glucuronic acid decarboxylase
Acc. AF506235		 107/107= mutant
0/42= wildtype
RT= no transcript detected		  
975   d1, eyes cyclopic. Nodal-related-1 (squint)
Acc. AF056327		 22/22= mutant
3/24= wildtype**		 B. Feldman, et al., Nature 395, 181-5. (1998)
* The word "necrosis" is used to denote cell death or degeneration and does not distinguish between apoptosis or other mechanisms of cell death
** This mutation is not fully penetrant.
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