GenMAPP, a new tool for viewing and analyzing microarray data on biological pathwayspp19 - 20 Kam D. Dahlquist, Nathan Salomonis, Karen Vranizan, Steven C. Lawlor
& Bruce R. Conklin doi:10.1038/ng0502-19 Full text|PDF
(59K)
AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34pp21 - 23 Anil K. Agarwal, Elif Arioglu, Salome de Almeida, Nurullah Akkoc, Simeon I. Taylor, Anne M. Bowcock, Robert I. Barnes
& Abhimanyu Garg Published online: 22 April 2002|doi:10.1038/ng880 Abstract|Full text|PDF
(194K)
|Supplementary Information
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesispp25 - 32 Paul D. Gottlieb, Stephanie A. Pierce, Robert J. Sims III, Hiroyuki Yamagishi, Elizabeth K. Weihe, June V. Harriss, Shanna D. Maika, William A. Kuziel, Heather L. King, Eric N. Olson, Osamu Nakagawa
& Deepak Srivastava Published online: 01 April 2002|doi:10.1038/ng866 Abstract|Full text|PDF
(1,205K)
Polygenic susceptibility to breast cancer and implications for preventionpp33 - 36 Paul D.P. Pharoah, Antonis Antoniou, Martin Bobrow, Ron L. Zimmern, Douglas F. Easton
& Bruce A.J. Ponder Published online: 04 March 2002|doi:10.1038/ng853 Abstract|Full text|PDF
(423K)
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cellspp37 - 46 John D. Cleary, Kerrie Nichol, Yuh-Hwa Wang
& Christopher E. Pearson Published online: 22 April 2002|doi:10.1038/ng870 Abstract|Full text|PDF
(1,104K)
See also:News and Views by Mirkin & Smirnova
Disruption of CREB function in brain leads to neurodegenerationpp47 - 54 Theo Mantamadiotis, Thomas Lemberger, Susanne C. Bleckmann, Heidrun Kern, Oliver Kretz, Ana Martin Villalba, François Tronche, Christoph Kellendonk, Daniel Gau, Josef Kapfhammer, Christiane Otto, Wolfgang Schmid
& Günther Schütz Published online: 22 April 2002|doi:10.1038/ng882 Abstract|Full text|PDF
(1,406K)
|Supplementary Information
Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutationspp55 - 59 The : : Hanne Meijers-Heijboer, Ans van den Ouweland, Jan Klijn, Marijke Wasielewski, Anja de Snoo, Rogier Oldenburg, Antoinette Hollestelle, Mark Houben, Ellen Crepin, Monique van Veghel-Plandsoen, Fons Elstrodt, Cornelia van Duijn, Carina Bartels, Carel Meijers
& Mieke Schutte: Lesley McGuffog, Deborah Thompson
& Douglas F. Easton: Nayanta Sodha, Sheila Seal, Rita Barfoot, Jon Mangion, Jenny Chang-Claude, Diana Eccles, Rosalind Eeles, D Gareth Evans, Richard Houlston, Victoria Murday, Steven Narod, Tamara Peretz, Julian Peto, Catherine Phelan, Hong Xiang Zhang, Csilla Szabo, Peter Devilee, David Goldgar, P Andrew Futreal, Katherine L. Nathanson, Barbara L. Weber, Nazneen Rahman
& Michael R. Stratton Published online: 22 April 2002|doi:10.1038/ng879 Abstract|Full text|PDF
(109K)
See also:News and Views by Brody
Topological and causal structure of the yeast transcriptional regulatory networkpp60 - 63 Nabil Guelzim, Samuele Bottani, Paul Bourgine
& François Képès Published online: 22 April 2002|doi:10.1038/ng873 Abstract|Full text|PDF
(680K)
|Supplementary Information
Network motifs in the transcriptional regulation network of Escherichia colipp64 - 68 Shai S. Shen-Orr, Ron Milo, Shmoolik Mangan
& Uri Alon Published online: 22 April 2002|doi:10.1038/ng881 Abstract|Full text|PDF
(1,629K)
|Supplementary Information
Regulation of noise in the expression of a single genepp69 - 73 Ertugrul M. Ozbudak, Mukund Thattai, Iren Kurtser, Alan D. Grossman
& Alexander van Oudenaarden Published online: 22 April 2002|doi:10.1038/ng869 Abstract|Full text|PDF
(159K)
See also:News and Views by Hasty & Collins
Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndromepp74 - 78 Gayle B. Collin, Jan D. Marshall, Akihiro Ikeda, W. Venus So, Isabelle Russell-Eggitt, Pietro Maffei, Sebastian Beck, Cornelius F. Boerkoel, Nicola Sicolo, Mitchell Martin, Patsy M. Nishina
& Jürgen K. Naggert Published online: 08 April 2002|doi:10.1038/ng867 Abstract|Full text|PDF
(592K)
|Supplementary Information
Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndromepp79 - 83 Tom Hearn, Glenn L. Renforth, Cosma Spalluto, Neil A. Hanley, Karen Piper, Sarah Brickwood, Chris White, Vincent Connolly, James F.N. Taylor, Isabelle Russell-Eggitt, Dominique Bonneau, Mark Walker
& David I. Wilson Published online: 08 April 2002|doi:10.1038/ng874 Abstract|Full text|PDF
(1,167K)
|Supplementary Information
Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse developmentpp84 - 88 Karen Niederreither, Suzan Abu-Abed, Brigitte Schuhbaur, Martin Petkovich, Pierre Chambon
& Pascal Dollé Published online: 15 April 2002|doi:10.1038/ng876 Abstract|Full text|PDF
(973K)
|Supplementary Information See also:News and Views by Perlmann
Segregation at three loci explains familial and population risk in Hirschsprung diseasepp89 - 93 Stacey Bolk Gabriel, Rémi Salomon, Anna Pelet, Misha Angrist, Jeanne Amiel, Myriam Fornage, Tania Attié-Bitach, Jane M. Olson, Robert Hofstra, Charles Buys, Julie Steffann, Arnold Munnich, Stanislas Lyonnet
& Aravinda Chakravarti Published online: 15 April 2002|doi:10.1038/ng868 Abstract|Full text|PDF
(939K)
|Supplementary Information See also:News and Views by Passarge
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase−deficient micepp94 - 99 Alberto M. Pendás, Zhongjun Zhou, Juan Cadiñanos, José M.P. Freije, Jianming Wang, Kjell Hultenby, Aurora Astudillo, Annika Wernerson, Francisco Rodríguez, Karl Tryggvason
& Carlos López-Otín Published online: 01 April 2002|doi:10.1038/ng871 Abstract|Full text|PDF
(866K)
|Supplementary Information
Evidence of en bloc duplication in vertebrate genomespp100 - 105 Laurent Abi-Rached, André Gilles, Takashi Shiina, Pierre Pontarotti
& Hidetoshi Inoko Published online: 22 April 2002|doi:10.1038/ng855 Abstract|Full text|PDF
(1,039K)
|Supplementary Information
Cardiac troponin T is essential in sarcomere assembly and cardiac contractilitypp106 - 110 Amy J. Sehnert, Anja Huq, Brant M. Weinstein, Charline Walker, Mark Fishman
& Didier Y. R. Stainier Published online: 22 April 2002|doi:10.1038/ng875 Abstract|Full text|PDF
(2,769K)
|Supplementary Information
-cell−specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter -cell masspp111 - 115 Rohit N. Kulkarni, Martin Holzenberger, David Q. Shih, Umut Ozcan, Markus Stoffel, Mark A. Magnuson
& C. Ronald Kahn Published online: 01 April 2002|doi:10.1038/ng872 Abstract|Full text|PDF
(1,779K)
-cell−specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter 
