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Nature Genetics  30, 350 - 351 (2002)
doi:10.1038/ng0402-350

Evaluating adaptive evolution

Shozo Yokoyama

Department of Biology, Syracuse University, Syracuse, New York 13244, USA. syokoyam@mailbox.syr.edu

Using comparative sequence analyses, we can identify proteins that may have been subject to positive darwinian selection. To test these statistical results, it is important to develop functional assays and identify amino-acid changes that are responsible for the adaptation of organisms to specific environments. One of the two duplicated pancreatic ribonuclease genes of a leaf-eating colobine monkey, douc langur, is now shown to have adapted to digest bacterial RNAs in the monkey's foregut.

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The origin of new genes: glimpses from the young and old
Nature Reviews Genetics Review (01 Nov 2003)

RESEARCH
Adaptive evolution of a duplicated pancreatic ribonuclease gene in a leaf-eating monkey
Nature Genetics Letters (01 Apr 2002)

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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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