Access

Letter

Nature Genetics 30, 233–237 (1 February 2002) | doi:10.1038/ng826

Identification of a variant associated with adult-type hypolactasia

Nabil Sabri Enattah , Timo Sahi , Erkki Savilahti , Joseph D. Terwilliger , Leena Peltonen & Irma J|[auml]|rvel|[auml]|

Adult-type hypolactasia, also known as lactase non-persistence (lactose intolerance), is a common autosomal recessive condition resulting from the physiological decline in activity of the lactase-phlorizin hydrolase (LPH) in intestinal cells after weaning. LPH hydrolyzes lactose into glucose and galactose.